7 proven effects and benefits of CBD (+ side effects)


Cannabidiol is a popular natural remedy used for many common ailments. Better known as CBD, it is one of the 100 chemicals known as cannabinoids found in the cannabis plant, Cannabis sativa. (Pubmed 1)

Tetrahydrocannabinol (THC) is the main psychoactive cannabinoid found in cannabis and causes the feeling of “high” often associated with cannabis. However, unlike THC, CBD is not psychoactive.

Buying CBD is a great option for those looking for relief from pain and other symptoms without the mind-altering effects of the herb or certain pharmaceutical drugs.

CBD oil is made by extracting the CBD from the cannabis plant and then diluting it with a carrier oil like coconut or hemp oil. It is gaining momentum in the world of health and wellness, some scientific studies confirm that it can relieve symptoms of diseases like chronic pain and anxiety.

Here are seven effects of CBD on health potentially proven by scientific studies. All information in this article is supported by official US scientific studies but should not be taken as definitive. Indeed, although the French state and the Ministry of Health are committed to starting a medical cannabis testing program, it is currently prohibited to promote potential beneficial effects of CBD as long as the information has not been officially ruled by the state.

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Cannabis has been used to treat pain as early as 2900 BC. JC. (Pubmed 2) More recently, scientists have discovered that certain components of cannabis, including CBD, are responsible for its pain-relieving effects. The human body contains a specialized system called the endocannabinoid system (ECS), which is involved in the regulation of various functions, including sleep, appetite, pain, and the immune system response. (Pubmed 3)

The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in your nervous system. Studies have shown that CBD can help reduce chronic pain by affecting endocannabinoid receptor activity, reducing inflammation, and interacting with neurotransmitters. (Pubmed 4)

For example, one study of effects in rats found that injections of CBD reduced the pain response to the surgical incision, while another study in rats found that oral treatment with CBD significantly reduced pain. and inflammation of the sciatic nerve. (Pubmed 5 and 6)

Several human studies have shown that a combination of CBD and THC is effective in treating pain associated with multiple sclerosis and arthritis. An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain associated with multiple sclerosis. A study of 47 people with multiple sclerosis looked at the effects of taking Sativex for one month. Participants saw improvement in pain, walking, and muscle spasms. However, the study did not include any control group and the placebo effects cannot be excluded. (Pubmed 7)

Another study found that Sativex significantly improved pain during movement, pain at rest and quality of sleep in 58 people with rheumatoid arthritis. (Pubmed 8)


CBD, especially in combination with THC, may be effective in reducing pain associated with conditions like multiple sclerosis and rheumatoid arthritis.


Anxiety and depression are common mental health disorders that can have devastating effects on health and well-being. According to the World Health Organization, depression is the leading contributor to disability worldwide, while anxiety disorders rank sixth. (WHO 9)

Anxiety and depression are usually treated with pharmaceutical drugs, which can cause a number of side effects, including drowsiness, restlessness, insomnia, sexual dysfunction, and headaches. (Pubmed 10)

In addition, drugs like benzodiazepines can be addictive and lead to addiction. (Pubmed 11) CBD oil has shown promise as a treatment for both depression and anxiety, which has led many people with these disorders to take an interest in this natural approach.

In a Brazilian study, 57 men were given oral CBD or a placebo 90 minutes before undergoing a mock public speaking test. Researchers found that a dose of 300 mg of CBD was the most effective in significantly reducing anxiety during the test. Placebo, one fake dose of 150 mg of CBD, and another fake dose of 600 mg of CBD had little or no effect on anxiety. Pubmed 12

CBD oil has even been used to safely treat insomnia and anxiety in children with post-traumatic stress disorder. (Pubmed 13) CBD has also shown antidepressant-like effects in several animal studies (Pubmed 14, Pubmed 15).

These qualities are linked to the ability of CBD to act on brain receptors for serotonin, a neurotransmitter that regulates mood and social behavior.

Read also: Where to Buy CBD in France?


The answer is yes. The use of CBD has been shown to reduce anxiety and depression in human and animal studies.


CBD may help reduce cancer symptoms and side effects from cancer treatment, such as nausea, vomiting, and pain. One study looked at the effects of CBD and THC in 177 people with cancer pain who did not experience relief from conventional pain relievers. Those treated with an extract containing both compounds experienced a significant reduction in pain compared to those who received only THC extract. (Pubmed 16)

CBD may also help reduce chemotherapy-induced nausea and vomiting, which are among the most common side effects of chemotherapy in people with cancer. (Pubmed 17)

While there are medications that help relieve these distressing symptoms, sometimes they are ineffective, leading some people to seek alternatives. A study of 16 people undergoing chemotherapy found that a one-to-one combination of CBD and THC given by mouth spray reduced chemotherapy-related nausea and vomiting better than standard treatment alone. (Pubmed 18)

Some test-tube and animal studies have even shown that CBD may have anti-cancer properties. For example, a test tube study found that concentrated CBD induced cell death in human breast cancer cells. (Pubmed 19)

Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice. (Pubmed 20)

However, these are test tube and animal studies, so they can only suggest what might work in humans. More studies in humans are needed before any conclusions can be drawn.

Read also: CBG: better than CBD? (explanations)

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Although CBD has been shown to help reduce symptoms related to cancer and cancer treatment in animals and test tubes, more research is needed to assess its effectiveness and safety in humans.


Acne is a common skin condition that affects over 9% of the population. (Pubmed 21) It is thought to be caused by a number of factors, including genetics, bacteria, underlying inflammation, and overproduction of sebum, an oily secretion produced by the sebaceous glands in the skin. (Pubmed 22 and 23)

Based on recent scientific studies, CBD oil may help treat acne due to its anti-inflammatory properties and ability to reduce sebum production. A test-tube study found that CBD oil prevented sebaceous gland cells from secreting excess sebum, exerted anti-inflammatory actions, and inhibited the activation of “pro-acne” agents like inflammatory cytokines. (Pubmed 24)

Another study came up with similar results, concluding that CBD may be an effective and safe way to treat acne, in part thanks to its remarkable anti-inflammatory qualities. (Pubmed 25)

While these results are promising, human studies exploring the effects of CBD on acne are needed.


CBD may have beneficial effects on acne due to its anti-inflammatory qualities and its ability to control the overproduction of sebum by the sebaceous glands.


Researchers believe that CBD’s ability to act on the endocannabinoid system and other brain signaling systems may be beneficial for people with neurological conditions. In fact, one of the most studied uses of CBD is in the treatment of neurological disorders like epilepsy and multiple sclerosis.

Although research in this area is still relatively recent, several studies have shown promising results. Sativex, an oral spray composed of CBD and THC, has been shown to be a safe and effective way to reduce muscle spasticity in people with multiple sclerosis. One study found that Sativex reduced spasms in 75% of 276 people with multiple sclerosis who suffered from drug-resistant muscle spasticity. (Pubmed 26)

Another study gave 214 people with severe epilepsy 0.9 to 2.3 grams of CBD oil per pound (or 2 to 5 g / kg) of body weight. Their seizures were reduced by a median of 36.5%. (Pubmed 27) Another study found that CBD oil significantly reduced seizure activity in children with Dravet syndrome, a complex childhood epilepsy disorder, compared to a placebo. (Pubmed 28) However, it’s important to note that some people in these two studies experienced side effects associated with CBD treatment, such as seizures, fever, and fatigue.

CBD has also been researched for its potential effectiveness in treating several other neurological diseases. For example, several studies have shown that treatment with CBD improves the quality of life and the quality of sleep in people with Parkinson’s disease. (Pubmed 29) (and 30)

What’s more, animal and test-tube studies have shown that CBD can reduce inflammation and help prevent neurodegeneration associated with Alzheimer’s disease. (Pubmed 31)

In a long-term study, researchers gave CBD to mice genetically predisposed to Alzheimer’s disease, finding that it …


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